1. Wait Wait Don't Tell Me
The "NPR News Quiz". Hilarious.
2. Wire Tap with Jonathan Goldstein
From CBC radio. You may know Goldstein from This American Life, on which is has been an occasional contributor. Good stories and cast of characters
3. The Onion Radio News
Fake headlines from the funniest site on the internet
4. Radio Lab
From WNYC. Science and other phenomena explored and sometimes explained in an entertaining fashion. Radio Lab expertly combines the two things I like in a podcast!
5. The Moth
The Moth "features true stories told live without notes". People telling tales from their lives to a group of strangers. Sometimes they are fantastic and almost always compelling.
6. Planet Money
From NPR. Economics explained (mostly)
7. This American Life
From PRI. An in depth look at a variety of topics, often funny or touching and always poignant.
8. The New Yorker Fiction
The best writing read to you by great performers. What's not to like?